П. Димитрова, С. Поповска, И. Иванов

Номер на Статия: 479 (Suppl 1):S1–S320; PS-02-009, S68 IF 3.5 Q1

27 Август 2021

Богомилова Камбурова З, Поповска С., Ковачева К., Петров К., Николова С.

Номер на Статия: 39 IF 2.3 Q1

14 Март 2022

Lynch syndrome (LS) is the most common hereditary cause of colorectal cancer (CRC), accounting for 3-5% of all CRC cases. LS was previously termed hereditary nonpolyposis CRC (HNPCC) to emphasize the absence of colon polyps and to distinguish it from the other types of hereditary CRC, which are characterized by the presence of polyps, such as Adenomatous Polyposis Coli and Hamartomatous Polyposis syndrome.

Комса-Пенкова Р., Стойчева С., Тончев П., Ставрева Г., Тодинова С., Георгиева Г., Йорданова А., Кюркчиев С., Алтанков Г.

Номер на Статия: 3957. IF 4,207 Q1

22 Септември 2022

Collagens are the most abundant proteins of the extracellular matrix (ECM) and are important for the mechanical properties of connective tissues, regulation of cell function, and communication. It recently became clear that they are also tightly involved in the regulation of adult stem cell functioning, such as renewal and differentiation. 

Комса-Пенкова Р., Данаилова А., Крумова С., Георгиева Г., Гьошева И., Гарчева Л, Илиев И., Гарчев Е., Керчева К., Савов А., Тодинова С.

Номер на Статия: Int. J. Mol. Sci.2022, 23(15), 8764 IF 6.208 Q1

6 Август 2022

Early pregnancy loss (EPL) or fetal loss is a relatively common pathology. Some of the causes of fetal loss include chromosomal abnormalities, genetic syndromes, thrombophilia, infections, antiphospholipid syndrome, and maternal diseases such as diabetes and hypertension, and inflammation. Nevertheless, more than 50% of EPLs remain idiopathic. Despite a wide range of investigations, no specific biomarkers with a high predictive value of threatening pregnancy losses have been identified.

Комса-Пенкова Р., Данаилова А., Крумова С., Георгиева Г., Гьошева И., Гарчева Л., Илиев И., Гарчев Е., Керчева К., Савов А., Тодинова С.

Номер на Статия: Int. J. Mol. Sci. 2022, 23, 4512. IF 6.208Q1

19 Април 2022

Early pregnancy loss (EPL) or spontaneous abortion is the most common complication of human reproduction, with an incidence ranging between 50–70% of all conceptions. EPL is usually associated with genetic or chromosomal abnormalities in the developing embryo, viral infections, immunological and immunogenic causes , thrombophilia, endocrine disorders , poorly controlled type 1 diabetes  and obesity. However, nearly 50% of the cases are idiopathic (due to unknown etiology).

Комса-Пенкова Р., Ставрева Г., Белемезова К., Кюркчиев С., Тодинова С., Алтанков Г.

Номер на Статия: Int J Mol Sci. 2022 Mar 11;23(6):3058. IF 6.208 Q1

11 Март 2022

In addition to their regenerative activity, mesenchymal stem cells (MSCs) are highly involved in extracellular matrix (ECM) remodeling . MSCs are multipotent stem cells (often referred to as adult stem cells) residing in most tissues poised to repair damage associated with trauma and ageing . As such, they are of great interest for most cell-based therapies . Adipose tissue-derived MSCs’ (ADMSCs) diverse differentiation capacity and immunomodulatory activity combined with their relative abundance, accessibility and low donor site morbidity render them particularly attractive therapeutic agents.

Регина Комса-Пенкова; Аделина Йорданова; Пенчо Тончев; Станимир Кюркчиев; Светла Тодинова; Величка Стрийкова; Марио Илиев; Борислав Димитров; Георги Алтанков

Номер на Статия: Int. J. Mol. Sci. 2023, 24, 3635. IF 4.67 Q1

11 Февруари 2023

The extracellular matrix (ECM) initiates several mechanical cues that are able to activate intracellular signaling events through cell–matrix interactions. It is generally agreed that the quality and quantity of ECM determine its physical parameters, affecting cellular response, which also applies to the behavior of stem cells . Each organ or tissue provides specific mechanical cues that have to be understood in the context of the entire multicellular organization.

М. Караманлиев, Д. Димитров

Номер на Статия: 24: 48-294.Q1

13 Септември 2022

Questionnaires were filled from 15 patients (93.75%), two patients were operated on in less than 3 months and did not fill the postoperative questionnaires. A total of 13 patients were included in the analysis. We analyzed the results from the preoperative questionnaire and the last available one.

Т. Калинов, Т. Георгиев, К. Близнакова, А. Златаров, Н. Колев

Номер на Статия: e12839 3,4 Q1

Януари 2023

Nowadays, in Bulgaria there is a trend of increasing entry into the surgical field of robot-assisted surgery operations, which suggests a need for the establishment of a large number of specialists in this field in a short period. Based on these arguments, the Medical University of Varna was the first university in the country to introduce a robotic surgery training program for medical students. The study aims to investigate the medical students’ satisfaction on robotic surgery training provided at Medical University of Varna with da Vinci Skills Simulator.

Blood Plasma Calorimetric Profiles of Women with Preeclampsia: Effect of Oxidative Stress

Регина Комса-Пенкова; Сашка Крумова; Ариана Лангари; Ина Гьошева; Лидия Гарчева; Августина Данаилова; Лора Топалова; Таня Стоянова; Величка Стрийкова; Алексей Савов и Светла Тодинова

Номер на Статия: IF 6,2 Q1

12 Февруари 2023

Purse-string failure at the beginning of the learning curve in transanal total mesorectal excision. European Journal of Surgical Oncology

Марин Караманлиев, Цветомир Иванов, Цанко Йоцов, Емил Филипов, Ташко Делийски, Добромир Димитров

Номер на Статия: Volume 47, Issue 2, e49. Q1